Oestrogel Gel for Hormone Replacement Therapy
Oestrogel
Gel (Estradiol Valerate), Progynova are a
hormone replacement therapy (HRT) used to substitute for the lack of oestrogen
production by the ovaries that happens during menopause or following surgical
removal of the ovaries, to relieve moderate to severe symptoms of menopause
caused by oestrogen deficiency, such as hot flushes, night sweats,
sleeplessness, vaginal dryness, headaches.
How
does Oestrogel work?
Oestrogel
contains the active ingredient estradiol which is a naturally occuring form of
the main female sex hormone, oestrogen.
Womens'
ovaries gradually produce less and less Oestrogen in the period up to the
menopause, and Oestrogen blood levels decline as a result. The declining levels
of oestrogen can cause distressing symptoms, such as irregular periods, hot
flushes, night sweats, mood swings and vaginal dryness or itching.
Oestrogen can
be given as a supplement to replace the falling levels in the body and help
reduce these distressing symptoms of the menopause. This is known as hormone
replacement therapy (HRT). HRT is usually only required for short-term relief
from menopausal symptoms.
Common
side effects
- Vomiting, Nausea
- Abdominal bloating
- Acne
- Altered menstrual cycle
- Absence of menstrual periods
- Ankle swelling
- Limb swelling
- Breast tenderness & enlargement
- Change in appetite
- Dark skin patches
- Difficulty in wearing contact lenses
- Hair loss, Weight loss, Weight gain
- Stomach cramp
- Vaginal discharge & Vaginal itching
Warning
Estrogens, either used alone or with another hormone
(progestin), have rarely caused very serious side effects. Discuss the risks
and benefits of hormone treatment with your doctor. Estrogens should not be
used to prevent heart disease or dementia.Estrogens can increase the risk of
cancer of the uterus (endometrial cancer). Taking a progestin as directed by your
doctor can help decrease this risk.
Tell your doctor right away if you have any
unusual vaginal bleeding.In postmenopausal women, estrogens can increase the
risk of cancer of the ovaries, stroke, dementia, and serious blood clots in the
legs. Estrogens alone do not appear to increase the risk of breast cancer when
used for up to 7 years. Estrogen, when used with a progestin, can increase the
risk of heart disease (such as heart attacks), stroke, serious blood clots in
the lungs/legs, dementia, and cancer of the breast/ovaries.
From
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